Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional)
This notice of funding opportunity (NOFO) uses a R61/R33 Phased Innovation Award activity code to support clinical research applications that are exploratory and developmental in nature and focus on understanding the neurobiological mechanisms underlying substance use disorders (SUD), including fundamental circuitry and behavior relevant to substance use. For projects not requiring a phased research approach, applicants are encouraged to apply under a different funding activity code (e.g., PA-25-305 "Research Project Grant (Parent R01 Clinical Trial Required)" or its subsequent reissue).
From Grants.gov — open and forecasted opportunities (grants.gov). First seen Oct 10, 2026.
Details
- Agency
- National Institutes of HealthFind in source ↗
- Closes
- Jun 16, 2028Find in source ↗
- Posted
- Aug 31, 2026Find in source ↗
- Opportunity number
- PAR-27-053Find in source ↗
- Assistance listing (ALN)
- 93.279Find in source ↗
- Eligible applicants
- Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; Private institutions of higher education; Small businesses; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; State governments; Independent school districts; Public and State controlled institutions of higher educationFind in source ↗
- Eligibility notes
- Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.Find in source ↗
- Category
- HealthFind in source ↗
- Funding type
- GrantFind in source ↗
History
No changes since GrantScout first read this opportunity on Oct 10, 2026.
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