NINDS Efficacy and Exploratory Clinical Trials (UG3/UH3 - Clinical Trial Required)
This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated clinical trials to the National Institute of Neurological Disorders and Stroke (NINDS). These trials must address questions within the mission and research interests of the NINDS and may include studies of small molecules, biologics, devices as well as surgical, behavioral, diet-based, or rehabilitation therapies. Studies addressing neurological diseases and care across the lifespan are highly encouraged. This notice invites both early- and middle-phase exploratory clinical trials as well as later phase confirmatory Phase 3 or comparative effectiveness clinical trials.
From Grants.gov — open and forecasted opportunities (grants.gov). First seen Oct 10, 2026.
Details
- Agency
- National Institutes of HealthFind in source ↗
- Closes
- Mar 9, 2029Find in source ↗
- Posted
- Aug 31, 2026Find in source ↗
- Opportunity number
- PAR-27-065Find in source ↗
- Assistance listing (ALN)
- 93.853Find in source ↗
- Eligible applicants
- Independent school districts; State governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; County governments; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Private institutions of higher education; City or township governments; Native American tribal governments (Federally recognized)Find in source ↗
- Eligibility notes
- Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.Find in source ↗
- Category
- HealthFind in source ↗
- Funding type
- Cooperative AgreementFind in source ↗
History
No changes since GrantScout first read this opportunity on Oct 10, 2026.
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