Glioblastoma Therapeutics Network (GTN) (U19 Clinical Trial Required)
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for research on novel therapies for adult glioblastoma (GBM). The goal is to improve the treatment of adult GBM by developing novel effective agents that can cross the blood brain barrier (BBB) and testing them clinically. Successful early-stage trials of new drugs from this NOFO would transition seamlessly to later stage trials using well-established NCI clinical trial mechanisms. To implement this concept, a highly collaborative GBM Therapeutics Network (GTN) of cross-cutting teams will be established, each team capable of driving therapeutic agent(s) from pre-clinical development, through investigational new drugs (IND) studies, into pilot clinical studies in humans. Appropriate therapeutic agents include: (1) novel agents or (2) agents or combinations approved for other indications and repurposed for treatment of GBM following appropriate preclinical studies. The scope of the NOFO, from late pre-clinical through early (Phase 0/1) clinical studies, uniquely spans a gap in the GBM drug development process.
From Grants.gov — open and forecasted opportunities (grants.gov). First seen Oct 10, 2026.
Details
- Agency
- National Institutes of HealthFind in source ↗
- Closes
- Jan 11, 2027Find in source ↗
- Award ceiling
- $700,000.00Find in source ↗
- Award size
- $100K to $1MFind in source ↗
- Total program funding
- $4,400,000.00Find in source ↗
- Posted
- Aug 31, 2026Find in source ↗
- Opportunity number
- RFA-CA-27-005Find in source ↗
- Assistance listing (ALN)
- 93.394; 93.395Find in source ↗
- Eligible applicants
- Special district governments; Public housing authorities/Indian housing authorities; Private institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Independent school districts; City or township governments; State governments; For profit organizations other than small businesses; County governments; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Native American tribal governments (Federally recognized); Small businessesFind in source ↗
- Eligibility notes
- Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.Find in source ↗
- Category
- HealthFind in source ↗
- Funding type
- Cooperative AgreementFind in source ↗
History
No changes since GrantScout first read this opportunity on Oct 10, 2026.
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