Somatic Mosaicism across Human Tissues (SMaHT) Program: Experimental and Computational Technology Development (RM1 Clinical Trial Not Allowed)
The purpose of the Somatic Mosaicism across Human Tissues (SMaHT) Network is to advance discovery of biological processes and disease mechanisms mediated by somatic mutations in human tissues. Since 2023, the program has generated multi-omic somatic mutation datasets from standardized human tissues spanning all three germ layers. Building on the Stage 1 foundation, the NIH intends to issue a Notice of Funding Opportunity (NOFO)supporting Stage 2 of the SMaHT Experimental and Computational Technology Development initiative. The Experimental and Computational Technology Development initiative supports multidisciplinary development, optimization, validation, benchmarking, and dissemination of rigorous, cost-effective technologies for somatic mutation detection and functional interpretation. Awardees will collaborate with other SMaHT Stage 2 initiatives to incorporate validated technologies into production workflows, pipelines, data releases, and community resources.
From Grants.gov — open and forecasted opportunities (grants.gov). First seen Oct 10, 2026.
Details
- Agency
- National Institutes of HealthFind in source ↗
- Posted
- Sep 14, 2026Find in source ↗
- Opportunity number
- RFA-RM-28-017Find in source ↗
- Assistance listing (ALN)
- 93.310Find in source ↗
- Eligible applicants
- Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Private institutions of higher education; State governments; County governments; Native American tribal governments (Federally recognized); Small businesses; Special district governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; City or township governments; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Independent school districtsFind in source ↗
- Eligibility notes
- Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).Find in source ↗
- Category
- HealthFind in source ↗
- Funding type
- GrantFind in source ↗
History
No changes since GrantScout first read this opportunity on Oct 10, 2026.
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